​"Blood Glucose Level in High-Risk New-born Infants of High-Risk Diabetic Pregnancy"

Abstract

Introduction and Rationale: Infants of Diabetic Mothers (IDMs), particularly those categorized as high-risk, are highly susceptible to disturbances in glucose homeostasis immediately post-delivery. This research was driven by the imperative to precisely characterize the trajectory of blood glucose levels in this vulnerable population and to standardize effective management protocols. Methods: A [Specify study type, e.g., descriptive correlational or interventional] study design was employed in a Neonatal Intensive Care Unit (NICU) setting. The sample comprised high-risk newborns from mothers with poorly controlled or pre-existing diabetes. Frequent capillary blood glucose monitoring was conducted at specified intervals during the first 48 hours of life. Expected/Key Findings: The study is expected to identify a high incidence of transient neonatal hypoglycemia, and in some cases, sustained hyperglycemia, during the immediate post-natal period. Furthermore, the research aims to establish a correlation between specific maternal glycemic control parameters (e.g., HbA1c) and the severity and persistence of glucose instability in the neonates. Conclusion and Implications: The findings are crucial for developing evidence-based guidelines for the immediate and vigilant monitoring and timely intervention strategies for glucose derangements in high-risk IDMs, ultimately aiming to prevent long-term neurodevelopmental sequelae.

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